what-exactly-is-in-the-comirnaty-vaccine-updated-as-necessary

What Exactly Is in the COMIRNATY ‘Vaccine’? [Updated as Necessary]


Here is a detailed, relatively technical list of the ingredients that make up the COMIRNATY and Pfizer-BioNTech COVID-19 “vaccine.”


LINK TO FDA SUMMARY BASIS FOR REGULATION

COMIRNATY (International Nonproprietary Name or INN: TOZINAMERAN):

Each 0.3 mL dose of COMIRNATY contains:

-30 μg of mRNA encoding the spike glycoprotein of SARS-CoV-2

and the lipids:

-0.43 mg ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-
hexyldecanoate)

-0.05 mg 2-(polyethylene glycol 2000)-N,N-ditetradecylacetamide

-0.09 mg 1,2-distearoyl-sn-glycero-3-phosphocholine

-0.2 mg cholesterol

-0.01 mg potassium chloride

-0.01 mg monobasic potassium phosphate,

-2.52 mg sodium chloride

-0.07 mg dibasic sodium phosphate dihydrate

-6 mg sucrose.

-30μg of mRNA (messenger ribonucleic acid) encoding the full length SARS-CoV-2 spike glycoprotein derived from the Wuhan-Hu-1 isolate (GenBank QHD43416.1 and GenBank MN908947.3 respectively)

NOTE: In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene and is read by a ribosome—a macromolecular machine found within all cells that performs biological protein synthesis (mRNA translation)—in the process of synthesizing a protein.

The ribosome reads the sequence of the messenger RNA (mRNA) and, using the genetic code, translates the sequence of RNA bases into a sequence of amino acids.

NOTE: A glycoprotein is a molecule consisting of a protein and a carbohydrate. Glycoproteins play a key role in the body’s immune system.

NOTE: The antigen-coding RNA sequence is codon-optimized and contains two proline mutations.

GenBank QHD43416.1

https://www.ncbi.nlm.nih.gov/protein/1791269090

GenBank MN908947.3

https://www.ncbi.nlm.nih.gov/nuccore/MN908947.3

-0.43 mg ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)

((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), per its CAS number, is an ionizable aminolipid that is responsible for mRNA compaction. The lipid also aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization.

NOTE: An ionizable lipid is a class of lipid molecules which remain neutral at physiological pH, but are protonated at low pH, making them positively charged.

LINK TO TWEET / LINK TO MILLIPORE SIGMA

LINK TO MEDCHEMEXPRESS

LINK TO TWEET / LINK TO BROADPHARM PAGE

(SUPPORTING DATA LINK / SUPPORTING DATA LINK / SUPPORTING DATA LINK)

-0.05 mg 2-(polyethylene glycol 2000)-N

The lipid 2-(polyethylene glycol 2000)-N is a modified polymer of ethylene glycol. According to the CDC, ethylene glycol is “a useful industrial compound found in many consumer products.” These consumer products include “antifreeze, hydraulic brake fluids, some stamp pad inks, ballpoint pens, solvents, paints, plastics, films, and cosmetics.”

The CDC notes that ethylene glycol breaks down into “toxic compounds” in the body. Ethylene glycol and its toxic byproducts first affect the central nervous system (CNS), then the heart, and finally the kidneys. Ingesting enough can cause death. Ethylene glycol is odorless.

LINK TO NIH WEBPAGE

LINK TO THE CDC WEBPAGE

LINK TO ROYAL SOCIETY OF CHEMISTRY’S PAGE / LINK TO TWEET

-0.09mg 1,2-distearoyl-sn-glycero-3-phosphocholine

LINK TO TWEET / LINK TO PUBCHEM PAGE

LINK TO TWEET / LINK TO PUBCHEM PAGE

LINK TO TWEET / LINK TO CAYMAN CHEMICAL

N-ditetradecylacetamide

LINK TO TWEET / LINK TO BIOPHARMA PEG

LINK TO WHO EVIDENCE ASSESSMENT

0.2 mg cholesterol

LINK TO WIKIPEDIA PAGE

-0.01 mg potassium chloride

Potassium chloride, also known as potassium salt is a metal halide; that is, a compound between a halogen and metals. (Halogens are a group in the periodic table consisting of five or six chemically related elements: fluorine, chlorine, bromine, iodine, and astatine.) Potassium chloride is used as a medication to treat and prevent low blood potassium. “Side effects may include heart problems if given too quickly by injection into a vein. By mouth it can result in abdominal pain, peptic ulcer disease, or gastrointestinal bleeding. Greater care is recommended in those with kidney problems.” (From Wikipedia.)

LINK TO NIH PAGE ON POTASSIUM CHLORIDE

According to Shine Retrofits: “Metal halides are produced as a result of combining halogen with a metal. In metal halide lamps, that is normally metals that have been mixed with iodine or bromine. Additionally, the type of metal halides used helps determine the color temperature of the light emitted.”

-0.01 mg monobasic potassium phosphate

Potassium phosphate is a generic term for the salts of potassium and phosphate ions. Potassium phosphate is used in nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications.

Given as an oral medication potassium phosphate helps to control the amount of calcium in the body and urine. It does so by making the urine more acidic. It is specifically used to prevent calcium kidney stones.

Side effects when given orally include: Nausea, vomiting, diarrhea, dizziness, or headaches. Less frequent, yet more serious side effects include confusion, fast/irregular heartbeat, unusual weakness, tingling/numbness of the hands/feet, signs of kidney problems (such as change in the amount of urine).

LINK TO TWEET / LINK TO HAZ-MAP PAGE

-2.52 mg sodium chloride

-0.07 mg dibasic sodium phosphate dihydrate

Sodium Phosphate Dibasic is a colorless, odorless, sand-like white powder or solid. It is used to make starch, as an emulsifier in foods, and in the production of enamels, detergents, and ceramics.

Side effects: Restaurant Norman notes that ingestion of sodium phosphate dibasic may cause irritation of the digestive tract. It also may be harmful if swallowed. If it’s inhaled, it may cause respiratory tract irritation.

According to Rugbank Online sodium phosphate dibasic “is an osmotic laxative used to cleanse the colon before a colonoscopy.”

LINK TO FDA SUMMARY BASIS FOR REGULATION

Feature image: Dirk Vorderstraße

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